Abstract: ObjectiveThe present study revealed the effects of different nitrogen application methods and irrigation amounts on agronomic characters,nutrient accumulation and yield of sugarcane, in order to provide reference for achieving high-yield and high-efficiency sugarcane cultivation through fertilizer resources. MethodWith ROC22 as test material, seven different treatments were conducted:no nitrogen and no water (CK), nitrogen as base fertilizer for one time, irrigation amount 750 mm(T1), nitrogen as base fertilizer for one time, irrigation amount 1000 mm(T2), nitrogen as base fertilizer for one time, irrigation amount 1250 mm(T3), nitrogen application for three times(base fertilizer 30%, nitrogen at tillering stage 30%and nitrogen at elongating stage 40%), irrigation amount 750 mm(T4), nitrogen application for three times, ir-rigation amount 1000 mm(T5), nitrogen application for three times, irrigation amount 1250 mm(T6). Agronomic characters, nutrient contents in different organs,yield and sugarcane juice brix were measured to study the effects of different nitrogen application methods and irrigation amounts on sugarcane growth and yield. ResultIn medium and large irrigation amounts treatments(1000 and 1250 mm, the same below), the plant heights of sugarcanes in three-time nitrogen applications treat-ments was higher than those in one-time nitrogen application , and the difference was significant between May to July (P<0.05). At maturity stage,dry weight of stalk was T1>T2>T3,T6>T4>T5,T1>T4,T2>T5,T3T4,T2>T5,T3T2>T3,T6>T4>T5,T1>T4,T2>T5,T3T1>T2,T4>T6>T5,T1