Abstract: Wild rice, with many superior traits and genes, has the closest relatives with cultivated rice ,which is the most important candidate for genetic improvement of cultivated rice. This article mainly reviewed the research progress and application of wild rice germplasm resources in conventional rice,three-line hybrid rice,two-line hybrid rice,and put for-ward some suggestions for high-yield rice breeding combining production practice:top-level design of scientific research system should be strengthened to allow the implementation of a certain number of middle and long term breeding programs , and create a favourable environment for cultivation of major varieties;cultivated rice with desired quality traits should be chosen for parents backcrossing and multi-crossing, or hybrid progenies with excellent traits in wild-cultivated derived population should conduct sib-crossing , so that superior genes of parents could combine in one cultivar; utilization of biological technologies such as embryo-rescue,transgene,pollen-tube import or ear-stem injection of wild rice DNA,MAS methods,construction of near isogenic lines and chromosome segment substitution lines with wild rice germplasm to use these excellent traits;research on basic theories using backbone parents materials and wild rice germplasm-derived lines, verification of high-yield QTL by MAS technique and promoted the application of genetic breeding projects in practice.