Abstract: Selenium is an essential trace nutrient for the human body， and it exhibits antioxidant， immunomodulatory， anti-inflammatory， and detoxification-supporting effects. Selenium-enriched agriculture， as an important branch of functional agriculture， is highly aligned with the diversified food supply system advocated by the comprehensive food vision. It demonstrates significant comprehensive value across three dimensions （health， economy， and ecology） not only expanding the boundaries of agriculture but also providing a new pathway for addressing global nutrition challenges. In terms of theoretical foundation， the integration of geology， environmental science and life sciences has established a robust theoretical framework for its sustainable development. In terms of technology system， selenium-enriched agriculture has formed a relatively comprehensive integrated technological system. Technologies such as soil-crop system regulation， artificial selenium enrichment， processing and testing， and blockchain technology-based traceability have been introduced into the selenium-enriched industry chain. These innovations enabled full-process traceability from production to consumption， enhancing product transparency and credibility. In terms of the supply and demand of selenium-enriched agricultural products， selenium industry in China was generally in an expansionary trend， yet with significant regional development disparities， influenced by regional distribution， product categories， consumer demand， and cognitive beha-vior. Selenium-enriched arable land in China exceeded 3.3333 million ha. A selenium-enriched agricultural layout system has been fundamentally established， dominated by natural selenium-enriched areas such as Enshi in Hubei， Ankang in Shaanxi， Guigang in Guangxi， Yichun and Wan’an in Jiangxi， Shitai in Anhui， Taoyuan and Xintian in Hunan. Its selenium-enriched brands have been currently upgrading from “resource dependency” to comprehensive competitiveness driven by “technology + standards + culture”. However， the development of selenium-enriched agriculture in China still faces numerous problems and challenges， including scientific and technological bottlenecks， inconsistent standards， market barriers， and industrial constraints. Therefore， it is necessary to promote the development of selenium-enriched agriculture in China toward standardization， high-endization， and branding through the deep integration of multiple disciplines such as agricultural science， nutrition science， and economics， as well as full-chain collaborative innovation from resource development to market application， thereby providing strategic support for building a sustainable development system and a healthy society： （1） interdisciplinary collaboration； （2） innovation in technical pathways； （3） promotion of industrial integration； （4） mutual recognition of standard formulation.