Abstract: Objective This study aimed to investigate the effects of different forest stands on soil quality and the growth and development of replanted Panax notoginseng （Burk.） F. H. Chen， so as to provide a scientific basis for its forest plantation and alleviating continuous cropping obstacles.Method Soil naturally air-dried for two years after Panax notoginseng （Burk.） F. H. Chen harvest was collected as control （CK）， and soil in which Pinus armandii Franch. （HX）， Platycladus orientalis （L.） Franco （CX）， and Pistacia weinmannifolia J. Poisson ex Franch. （QX） were planted for 2 years after Panax notoginseng （Burk.） F. H. Chen harvest was used as the experimental groups. A pot experiment was conducted to introduce different treatments using a inoculation method of 10%. The emergence rate， survival rate， root rot incidence rate， and dry weight were determined； soil physicochemical properties， enzyme activities， and metabolite profiles were also assessed to investigate the effects of different forest stand treatments on obstacles in continuous cropping links for Panax notoginseng （Burk.） F. H. Chen.Result Compared with CK， HX， CX， and QX treatments significantly increased emergence rates of replanted Panax notoginseng （Burk.） F. H. Chen by 12%， 25%， and 22% （P<0.05， the same below）， respectively， while survival rates increased by 22%， 32%， and 28%， and disease incidence rate decreased by 10%， 10%， and 8%. Moreover， the dry weight of aboveground per plant and the dry weight of belowground parts per plant increased significantly， by 59%， 30%， 20% and 44%， 59%， 26%， respectively. In the soil of HX， CX， and QX treatments， lower organic matter and available potassium content were significantly decreased， alkali-hydrolyzable nitrogen content was increased， and activities of urease， sucrase， and catalase were significantly enhanced. According to differential analysis of soil metabolites， 56 metabolites were detected and classified into nine categories， and 33 among them were identified as differential metabolites， which were mainly organic acids and their derivatives， oxygenated organics， lipids， and lipid-like compounds. Correlation analysis revealed that， under different forest stand treatments， the majority of these differential metabolites were positively correlated with root rot incidence rate and dry weight per plant of Panax notoginseng （Burk.） F. H. Chen.Conclusion Different forest stand treatments could improve soil environment， foster the growth of replanted Panax notoginseng （Burk.） F. H. Chen， and the continuous cropping obstacles of replanting Panax notoginseng （Burk.） F. H. Chen could be alleviated through regulating the composition of soil metabolites.